FDA-approved drug protects mice from Ebola
The recent Ebola outbreak in West Africa has claimed more than 11,300 lives and starkly revealed the lack of effective options for treating or preventing the disease. Progress has been made on...
View ArticleResearchers answer long-standing question about lupus
For years, biomedical researchers have suspected that a specific set of immune cells are responsible for causing disease in lupus patients, but until now they haven't known for sure one way or the other.
View ArticleStudy shows path to 'dial down' autoimmunity without compromising immune...
A new study led by scientists at The Scripps Research Institute (TSRI) shows how dangerous autoimmune responses, seen in diseases such as lupus and multiple sclerosis, might be "dialed down" without...
View ArticleTuning macrophages a 'breakthrough' in cancer immunotherapy
Similar to stem cells differentiating to make your body's tissues, the immune system's macrophages pick a life path, differentiating into macrophages that recruit resources for wound repair or...
View ArticleInterferon not beneficial for most stage III melanoma
Final results for the Sunbelt Melanoma Trial, published online this month in the Journal of Clinical Oncology, show that thanks to current diagnostic techniques, most stage III melanoma patients do not...
View ArticleNew understanding of TB could lead to personalised treatments
Tuberculosis (TB) used to kill one in seven people around the world before the advent of antibiotics. However the increasing prevalence of multi-drug resistant TB means that doctors are running out of...
View ArticleFingolimod in multiple sclerosis: No hint of added benefit in new therapeutic...
Since its approval in 2011, the multiple sclerosis drug fingolimod (Gilenya) has already undergone three early benefit assessments, all of which were mainly based on the approval study TRANSFORMS....
View ArticleResearchers find new clue in lupus autoantibody production
A signaling molecule called interferon gamma could hold the key to understanding how harmful autoantibodies form in lupus patients. The finding could lead to new treatments for the chronic autoimmune...
View ArticleNewly approved all-oral hep C combination drug found more effective in...
Findings presented today from a Phase 3 head-to-head study that compared two direct-acting antiviral treatment regimens, demonstrated that the all-oral, once daily combination of elbasvir and...
View ArticleStudy demonstrates benefits of existing treatment for hepatitis D patients
New research presented today shows that interferon alpha (IFNa) based therapies are effective in suppressing disease progression in a severe form of chronic viral hepatitis, Hepatitis delta.
View ArticlePotential first-in-class treatment is well-tolerated in patients with chronic...
New data presented today confirms that a novel first-in-class treatment for Hepatitis B, called NVR 3-778, is well-tolerated and can reduce levels of the virus' genetic material in the body when...
View ArticleResearchers discover potential genetic trigger of autoimmune disease
Researchers at Hospital for Special Surgery (HSS) have uncovered a potential genetic trigger of systemic autoimmune disease. The study, the culmination of more than 10 years of research and published...
View ArticleShocking new role found for the immune system: Controlling social interaction
In a startling discovery that raises fundamental questions about human behavior, researchers at the University of Virginia School of Medicine have determined that the immune system directly affects -...
View ArticleInterferon shows promise as flu therapy
A molecule the body produces naturally in response to virus infection could be a viable flu treatment in the future, suggest researchers at the Francis Crick Institute in London.
View ArticleScientists discover critical anti-viral role of biological molecule
Scientists have discovered that a biological molecule important in cell growth (STAT3) is also critical in protecting us against infection - so much so that we would be unable to fight the common flu...
View ArticleZika virus blindfolds immune alarm cells
Gatekeeper immune cells are fighting Zika virus with an arm tied behind their backs, scientists from Emory Vaccine Center report.
View ArticleStudy finds new clues to causes of heart failure
Of the more than 700,000 Americans who suffer a heart attack each year, about a quarter go on to develop heart failure. Scientists don't fully understand how one condition leads to the other, but...
View ArticleStressed out interferons reveal potential key to alternative lupus treatment
Only one new drug has become available over the past 50 years for the estimated 1.5 million Americans and five million-plus people worldwide suffering from lupus, but new research has identified a...
View Article'Smart' genetic library makes disease diagnosis easier
Researchers at Hiroshima University have developed a smart genetic reference library for locating and weeding out disease-causing mutations in populations.
View ArticleInterferon drug shows promise in treating Ebola
Toronto)—A pilot study of a class of drugs used to treat hepatitis and some forms of multiple sclerosis has been shown for the first time to ease symptoms of Ebola patients, while also increasing their...
View ArticleNew interferon shows promise against hepatitis B in cell culture, and animal...
Hepatitis B is notoriously difficult to eradicate with currently available agents.. Now, in a new study, a novel form of "pegylated" interferon-β has reduced hepatitis B virus (HBV) infections in...
View ArticleAnthrax spores use RNA coat to mislead immune system
Researchers from Harvard Medical School have discovered that the body's immune system initially detects the presence of anthrax spores by recognizing RNA molecules that coat the spores' surface. But...
View ArticleVirulence factor made by influenza virus is potential target for vaccine drug...
A new study describes how NS1, a protein produced by influenza A viruses, suppresses the body's immune responses to viral infection. Researchers present the potential to develop a live attenuated...
View ArticleCandida antigen safe, effective for treating common warts
(HealthDay)—Candida antigen is a promising, effective, and safe immunotherapeutic treatment for common warts, according to a study published online Aug. 8 in the International Journal of Dermatology.
View ArticleNew knowledge on how HIV beats the body's early immune response
In an important step towards eradicating HIV-associated viral reservoirs, researchers at Sydney's Westmead Institute for Medical Research have identified how the HIV virus hijacks the innate immune...
View ArticleSignal flare – how heart muscle cells protect themselves from viral invaders
The human heart is particularly vulnerable to viruses. That's because cardiac myocytes, the heart muscle cells that give your heart its ability to "beat," have one major weakness – they don't reproduce...
View ArticleImmune cells mistake heart attacks for viral infections
A study led by Kevin King, a bioengineer and physician at the University of California San Diego, has found that the immune system plays a surprising role in the aftermath of heart attacks. The...
View ArticleHow Zika infection drives fetal demise
A powerful antiviral protein may act as a checkpoint for keeping or ending a pregnancy.
View ArticleHepatitis therapy: Kupffer cells adjust the balance between pathogen control...
Inflammation of the liver can result from different causes. Besides infections with hepatitis B virus (HBV) and hepatitis C virus (HCV), other viruses such as cytomegalovirus (CMV) are able to trigger...
View ArticleNew approach could help curtail hospitalizations due to influenza infection
More than 700,000 Americans were hospitalized due to illnesses associated with the seasonal flu during the 2014-15 flu season, according to federal estimates. A radical new approach to vaccine...
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